Camel Milk as an Amazing Remedy for Health Complications

A Review

Authors

  • Tahereh Mohammadabadi Department of Animal Science, Faculty of Animal Science and Food Technology, Agricultural Sciences and Natural Resources University of Khuzestan, Ahvaz, Iran

DOI:

https://doi.org/10.37077/25200860.2020.33.2.11

Keywords:

Camel milk, Health, Lactoferrin, Medicinal values

Abstract

Camel milk has unique benefits for human health. Protein is the main component which gives special properties to camel milk and effectively influences its nutritional value. Due to lack of β-lactoglobulin in the camel milk, it may be as a proper alternative for human milk. Camel milk is rich in vitamins C, manganese and iron. There are high amount of unsaturated fatty acids, immunoglobulin’s, insulin like protein and protective enzymes like lactoferrin and lysozyme in the camel milk. The lactoferrin has the effects or properties of antibacterial, antiviral and anti-inflammatorry. Also, it has been proven that camel milk has beneficial application in disorders of stomach and intestinal, food allergy, diabetes mellitus, cancer, autism, and viral hepatitis. Camel milk containing insulin like protein and may help to heal diabetes of Type 1 and 2 and gestational diabetes. It contains small size immunoglobulins which strengthens the immune system. In addition, camel milk reduces blood cholesterol amount, avoiding of psoriasis disease, healing of inflammation and improving of tuberculosis patients. Camel milk may be effective as unique miracle in many healthy issues of human and especially cardiovascular system. Therefore, it is not only food, but also it is as amazing remedy for treatment and healthy issues.

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References

Agrawal, R. P., Jain, S., Shah, S., Chopra, A., & Agarwal, V. (2011). Effect of camel milk on glycemic control and insulin requirement in patients with type 1 diabetes: 2-years randomized controlled trial. European Journal Clinical Nutrition, 65, 1048-1052. https://doi.org/10.1038/ejcn.2011.98

Agrawal, R. P., Budania, S., Sharma, P., Gupta, R., & Kochar, D. K. (2007). Zero prevalence of diabetes in camel milk consuming Raica community of north-west Rajasthan, India. Diabetes Research and Clinical Practice, 76, 290e6.

Agrawal, R. P., Dogra, R., Mohta, N., Tiwari, R., Singhal, S., & Sultania, S. (2009). Ben¬eficial effect of camel milk in diabetic nephropathy. Acta Biomedica, 80, 131-134.

Agrawal, P. P., Swami, S. C., Beniwal, R., Kochar, D. K., Sahani, M. S., & Tuteja, F. C. (2003). Effect of camel milk on glycemic control, risk factors and diabetes quality of life in type-1 diabetes: A randomized prospective controlled study. Journal of Camel Practice and Research, 10, 45-50.

Al-Asmari, A. K., Abbasmanthiri, R., Al-Elewi, A. M., Al-Omani, S., Al-Asmary, S., & Al-Asmari, S.A. (2014). Camel milk beneficial effects on treating Gentamicin induced alterations in rats. Journal of Toxicology, 2014, 1-8.

Alavi, F., Salami, M., Emam-Djomeh, Z., Mohammadian, M. (2017). Nutraceutical Properties of Camel Milk. 451-468. In: Nutrients in Dairy and Their Implications for Health and Disease. Watson, R., Collier, R. & Preedy, V. Academic Press, Elsevier. 490pp.

Al-Ayadhi, L. Y., & Elamin, N. E. (2013). Camel milk as a potential therapy as an antioxidant in autism spectrum disorder (ASD). Evidence-Based Complementary and Alternative Medicine, 2013, 1-9. http://dx.doi.org/10.1155/2013/602834

Alhaj, O. A., Kanekanian, A., Peters, A. & Tatham A. S. (2010). Hypocholesterolaemic effect of Bifidobacterium animalis subsp. lactis (Bb12) and trypsin casein hydrolysate. Food Chemistry, 123: 430–435.

Al-Hashem, F. (2009). Camel’s milk protects against aluminum chloride-induced normocytic normocromic anemia, lipid peroxidation and oxidative stress in erythrocytes of white albino rats. American Journal of Biochemistry and Biotechnology, 5(3): 127-136.

Al-Humaid, A. I., Mousa, H. M., El-Mergawi, R. A., & Abdel-Salam, A. M. (2010). Chemical composition and antioxidant activity of dates and date scamel-milk mixtures as a protective meal against lipid peroxidation in rats. American Journal of Food Technology., 5(1): 22-30.Doi:10.3923/ajft.2010.22.30

Ali, A. A., Alyan, A. A., & Bahobail, A. S. (2013). Effect of fermented camel milk and cow milk containing (bifidobacteria) enriched diet in rats fed on cholesterol level. The Agricultural Science Research Journal, 3, 342e6.

Almahdy, O., El-Fakharany, E. M., El-Dabaa, E., Ng, T. B., & Redwan, E. M. (2011). Examination of the activity of camel milk casein against hepatitis C virus (Genotype-4a) and its apoptotic potential in hepatoma and HeLa cell lines. Hepatitis Monthly, 11, 724-730. https://doi.org/10.5812/kowsar.1735143X.722.

Al-Majali, A. M., Bani-Ismail, Z., Al-Hami, Y., & Nour, A. Y. (2007). Lactoferrin concentration in milk from camels (Camelus dromedaries) with and without subclinical Mastitis. The International Journal of Applied Research in Veterinary Medicine, 5, 120-124.

Al-Numair, K. S. (2010). Type II diabetic rats and the hypolipidemic effect of camel milk. The Journal of Food, Agriculture and Environment, 8, 77e81.

Al-Wabel, N. A., Hassan, A., Abbas, H., & Muosa, H. (2012). Antiulcerogenic effect of camel milk against ethanol induced gastric ulcers in rats. Webmed. Central Vet. Med.

Alwan, A., & Tarhuni, A. (2000). The effect of camel milk on Mycobacterium tuberculosis in man. 2nd International Camelid Conference: Agroeconomics of Camelid Farming, Almaty, Kazakhstan, 8-12.

Aqiba, A. I., Kulyar, Muhammad, F. A., Ashfaq, Kh., Bhutta, Z. A., Shoaib M., & Ahmed, R. (2019). Camel milk insuline: Pathophysiological and Molecular Repository. Trends in Food Science and Technology, 88: 497-504. https://doi.org/10.1016/j.tifs.2019.04.009

Ayoub, M. A., Palakkott, A. R., Ashraf, A., & Iratni, R. (2018). The molecular basis of the anti-diabetic properties of camel milk. Diabetes Research and Clinical Practice, 146, 305-312. https://doi.org/ 10.1016/j.diabres.2018.11.006

Ayyash, M. (2016). Investigating the antimicrobial activity of pasteurized and raw camel milk against foodborne pathogens: Listeria monocytogenes and E. coli O157:H7. Journal of Animal Science., 94: 239-239. https://doi.org/10.2527/jam2016-0498

Bölte, S., & Poustka, F. (2002). The relation between general cognitive level and adaptive behavior domains in individuals with autism with and without co-morbid mental retardation. Child Psychiatry and Human Development, 33, 165-172.

Babilas. P.; Knie, U. & Abels, C. (2012). Cosmetic and dermatologic use of alpha hydroxy acids. Journal der Deutschen Dermatologischen Gesellschaft., 10: 488-491. https://doi.org/10.1111/j.1610-0387.2012.07939.x

Baubekova, A., Kalimbetovaa, S. A., Akhmetsadykova, S. H., Konuspayeva, O., & Faye, B. (2015). Comparison of D. Lactate and L. lactate content in cow and camel milk. In: Almaty, K., Konuspayeva, G. (Eds.). Proceeding 4th Conferences of ISOCARD, Silk Road Camel: The Camelids, main stakes for sustainable development, June 8-12, Science Practical Journal Veterinary, 2, 397-398.

Cardoso, R.R.; Santos, R.M.; Cardoso, C.R. & Carvalho. M.O. (2010). consumption of camel’s milk by patients intolerant to lactose. A preliminary study. Revista alergia Mexico, 57, 26-32.

Choi, S.K.; Park, K.D.; Kim, D.A.; Lee, D.W. & KiM, Y.J. (2013). Preparation of camel milk liposome and its anti-aging effects. Journal of Society of cosmetic scientists of Korea., 40(2): 155-161. DOI: 10.15230/SCSK.2014.40.2.155

Conesa, C.; Sanchez, L.; Rota, C.; Perez, M.; Calvo M. & Farnoud S. (2008). Isolation of lactoferrin from milk of different species; calorimetric and antimicrobial studies. Comparative Biochemistry and Physiology., 150: 131-139. doi: 10.1016/j.cbpb.2008.02.005

Dallak, M. (2009). Camel’s milk protects against cadmium chloride-induced hypochromic microcytic anemia and oxidative stress in red blood cells of white albino rats. American Journal of Pharmacology and Toxicology., 4(4): 136-143. DOI: 10.3844/ajptsp.2009.136.143

Darwish, H.A.; Raboh, N.R.A. & Mahdy, A. (2012). Camel’s milk alleviates alcohol-induced liver injury in rats. Food and Chemical Toxicology., 50(5): 1377-1383. doi: 10.1016/j.fct.2012.01.016.

Ebaid, H.; Abdel-Salam, B.; Hassan, I.; Al-Tamimi, J.; Metwalli, A. & Alhazza, I. (2015). Camel milk peptide improves wound healing in diabetic rats by orchestrating the redox status and immune response. Lipids in Health and Disease., 14, 132. https://doi.org/ 10.1186/s12944-015-0136-9

Elagamy, E.I.; Nawar, M.; Shamsia. S.M.; Awad, S. & Haenlein, G.F. (2009). Are camel milk proteins convenient to the nutrition of cow milk allergic children? Small Ruminant Research., 82: 1-6. https://doi.org/10.1016/j.smallrumres. 2008.12.016

Elayan, A. A., Sulieman, A. E., & Saleh, F.A. (2008). The hypocholesterolemic effect of Gariss and Gariss containing Bifid bacteria in rats fed on a cholesterol-enriched diet. Asian Journal of Biochemistry., 3, 43-47. 10.3923/ajb.2008.43.47

El-Fakharany, E. M., Abedelbaky, N., Haroun, B. M., Sanchez, L., Redwan, N. A. E., & Redwan, M. (2012). Anti-infectivity of camel polyclonal antibodies against hepatitis C virus in Huh 7.5 hepatoma. Virology Journal., 16, 201-211.

El-Fakharany, E. M., Sánchez, L., Al-Mehdar, H. A., & Redwan, E. M. (2013). Effectiveness of human, camel, bovine and sheep lactoferrin on the hepatitis C virus cellular infectivity: comparison study. Virology Journal., 10, 1. https://virologyj.biomedcentral.com/articles/10.1186/1743-422X-10-199

Farah, Z. (1993). Composition and characteristics Camel milk. Journal of Dairy Research., 60, 603-26. https://doi.org/10.1017/S0022029900027953

Gader, A. G. M. A. & Alhaider, A. A. (2016). The unique medicinal properties of camel products: A review of the scientific evidence. Journal of Taibah University Medical Sciences., 11, 98-103. https://doi.org/10.1016/j.jtumed.2015.12.007

Galali, Y., & Al-Dmoor, A. (2019). Miraculous Properties of Camel Milk and Perspective of Modern Science. Journal of Family Medicine and Disease Prevention., 5: 95. https://doi.org/10.23937/2469-5793/1510095.

Gizachew, A.; Teha, J. & Birhanu, T. (2014). Review on medicinal and nutritional values of camel milk. Natural Sciences., 12(12): 35-40.

Gul, W., Farooq, N., Anees, D.; Khan, U., & Rehan, F. (2015). Camel Milk: A boon to mankind. International Journal of Research Studies in Biosciences., 11, 23-29.

Habib, H. M., Ibrahim, W. H., Schneider-Stock, R., & Hassan, H.M. (2013). Camel milk lactoferrin reduces the proliferation of colorectal cancer cells and exerts antioxidant and DNA damage inhibitory activities. Food Chemistry, 141, 148-152. https://doi.org/10.1016/j.foodchem.2013.03.039.

Hamad, E.M.; Abdel-Rahim, E.A.;& Romeih, E.A. (2011). Beneficial effect of camel milk on liver and kidneys function in diabetic Sprague-Dawley rats. International Journal of Dairy Science., 6, 190-197.

Hoelzer, W.; Muyldermans, S. & Wernery, U. (1998). A note on camel IgG antibodies. Journal of Camel Practice and Research., 5: 187-188.

Jilo, K. & Tegegne, D. (2016). Chemical Composition and Medicinal Values of Camel Milk. International Journal of Research Studies in Biosciences., 4, 13-25.

Kaskous, S. (2016). Importance of camel milk for human health. Emirates Journal of Food Agriculture, 26, 158-163. https://doi.org/10.9755/ejfa.2015-05-296.

Katz, Y.; Goldberg, M.R.; Zadik-Mnuhin, G.; Leshno, M. & Heyman, E. (2008). Cross-sensitization between milk proteins: reactivity to a “kosher” epitope? Israel Medical Association Journal., 10, 85-88. https://pubmed.ncbi.nlm.nih.gov/18300584/

Korashy, H.M.; Maayah, Z.H.; Abd-Allah, A.R.; El-Kadi, A.O. & Alhaider, A.A. (2012). Camel milk triggers apoptotic signaling pathways in human hepatoma HepG2 and breast cancer MCF7 cell lines through transcriptional mechanism. Journal of Biomedicine and Biotechnology., 2012: 9pp.

Korish, A. A., & Arafah, M.M. (2013). Camel milk ameliorates steatohepatitis, insulin resistance and lipid peroxidation in experimental non-alcoholic fatty liver disease. BMC Complementary and Alternative Medicine., 13, 1. https://doi.org/ 10.1186/1472-6882-13-264.

Levy, A., Steiner, L., & Yagil, R. (2013). Camel milk: disease control and dietary laws. Journal of Health Sciences., 1: 48- 53.

Li, H., & Papadopoulos, V. (1998). Peripheral-type benzodiazepine receptor function in cholesterol transport. Identification of a putative cholesterol recognition/interaction amino acid sequence and consensus pattern. Endocrinology., 139, 4991-4997. DOI:10.1210/endo.139.12.6390

Mohamad, R.H.; Zekry, Z.K.; Al-Mehdar, H.A.; Salama, O.; El-Shaieb, S.E. & El- Basmy, A.A. (2009). Camel milk as an adjuvant therapy for the treatment of type 1 diabetes: Verification of a traditional ethnomedical practice. Journal of Medicinal Food., 12, 461-465. https://doi.org/10.1089/jmf.2008.0009.

Mohamed, N. & Ali, S. (2008). Camel milk modulates gamma radiation induced biochemical hazardous changes in rats. Radiation Research., 40(4): 1013-1026. doi: 10.1017/dmp.2018.16

Molitch, M.E.; Defronzo, R.A.; Franz, M.J. & Keane, W.F. (2004). Nephropathy in diabetes. Diabetes Care., 27, S79. https://doi.org/10.2337/diacare.27.2007.S79

Morin, D.E.; Rowan, L.L. & Hurley, W.L. (1995). Comparative study of proteins, peroxidase activity and N-acetyl-ß-Dglucosaminidase activity in llama milk. Small Ruminant Research., 17, 255-261. https://doi.org/10.1016/0921-4488(95)00679-F

Mullaicharam, A.R. (2014). A review on medicinal properties of camel milk. World Journal of Pharmaceutical Sciences., 2, 237-242.

Muyldermans, S.; Cambillau, C. & Wyns, L. (2001). Recognition of antigens by single-domain antibody fractions: the superfluous luxury of paired domains. Trends in Biochemical Sciences., 26, 230-235. https://doi.org/10.1016/s0968-0004(01)01790-x

Panwar, R., Grover, C. R.; Kumar, V., Ranga, S. & Kuma, N. (2015). Camel milk: Natural medicine - Boon to dairy industry”. Principal Scientist; Ph. D. Scholars; Dairy Microbiology Division, ICAR-National Dairy Research Institute, Karnal, (Haryana)., 1-10.

Quan, S.; Tsuda, H. & Miyamoto, T. (2008). Angiotensin I-converting enzyme inhibitory peptides in skim milk fermented with Lactobacillus helveticus 130B4 from camel milk in Inner Mongolia, China. Journal of the Science of Food and Agriculture., 88, 2688-2692. https://doi.org/10.1002/jsfa.3394

Redwan, E.R.M. & Tabll, A. (2007). Camel lactoferrin markedly inhibits hepatitis C virus genotype 4 infection of human peripheral blood leukocytes. Journal of Immunoassay and Immunochemistry., 28: 267-277. https://doi.org/10.1080/15321810701454839

Rasheed, Z. (2011). Monitoring biodegradative enzymes with nanobodies raised in Camelus dromedaries with mixtures of catabolic proteins. Environmental Microbiology., 13: 960-974. https://doi.org/10.1111/j.1462-2920.2010.02401.x

Rasheed, Z. (2017). Medicinal values of bioactive constituents of camel milk: A concise report. International Journal of Health Sciences., 11(5):1-2.

Restani, P.; Gaiaschi, A.; Plebani, A.; Beretta, B.; Cavagni, G. & Galli, C. (1999). Cross reactivity between milk proteins from different animal species. Clinical and Experimental Allergy., 29: 997-1004.https://doi.org/10.1046/j.1365-2222.1999.00563.x

Russo, A.J. (2009). Decreased serum Cu/Zn SOD in children with autism. Nutrition and Metabolic Insights., 2: 27-35. DOI: 10.4137/NMI.S3733

Salami, M.; Moosavi-Movahedi, A.A.; Moosavi-Movahedi, F.; Ehsani, M.R. & Yousefi, R. (2011). Biological activity of camel milk casein following enzymatic digestion. Journal of Dairy Research., 78: 471-478. https://doi.org/10.1017/S0022029911000628

Saltanat, H.; Li, H.; Xu, Y.; Wang, J.; Liu, F. & Geng, XH. (2009). The influences of camel milk on the immune response of chronic hepatitis B. Xi bao yu fen zi mian yi xue za zhi= Chinese journal of cellular and molecular immunology., 25(5): 431-433.

Salwa, M.Q. & Lina, A.K. (2010). Antigenotoxic and anticytotoxic effect of camel milk in mice treated with cisplatin. Saudi Journal of Biological Sciences., 17(2): 159-166. https://doi.org/10.1016/j.sjbs.2010.02.010

Sboui, A.; Khorchani, T. & Djegham, M. (2010). Anti-diabetic effect of camel milk in alloxan-induced diabetic dogs: A dose-response experiment. Journal of Animal Physiology and Animal Nutrition., (Berl), 94: 540-546. https://doi.org/10.1111/j.1439-0396.2009.00941.x

Shabo. Y. & Yagil, R. (2005). Etiology of autism and camel milk as therapy. International Journal on Disability and Human Development., 4: 67-70. https://doi.org/10.1515/IJDHD.2005.4.2.67

Shamsia, S.M. (2009). Nutritional and therapeutic properties of camel and human milks. Journal of Genetics and Molecular Biology., 1: 52.

Shori, A.B. (2015). Camel milk as a potential therapy for controlling diabetes and its complications: A review of in vivo studies. Journal of Food and Drug Analysis., 23: 609-618. https://doi.org/10.1016/j.jfda.2015.02.007.

Stahl, T. (2005). Vitamingehalte und Fettsäuremuster in Kamelmilch. Ph. D Thesis. Univ. Giessen, 147pp.

Wernery, R. & Yagil, R. (2012). Medicinal properties in camel milk for treatment of Epidemic Diseases. Proc. 3rd ISOCARD Int. Conf., 29th January- 1st February 2012 Muscat, Sultanate of Oman. 225-227.

Wernery, U. (2006). Camel milk, the white gold of the desert. J. Camel Pract. Res., 13(1): 15-26. https://www.researchgate.net/publication/279892395_Camel_milk_the_white_gold_of_the_desert

Wild, S., Roglic, G., Green, A., Sicree, R., & King, H. (2004). Global prevalence of diabetes: Estimates for the year 2000 and projections for 2030. Diabetes Care, 2, 1047-1053.

Yagil, R. (2013). Camel milk and its unique anti-diarrheal properties. Israel Medical Association Journal., 15: 35-36.

Yagil, R. (2017). Cosmeceuticals: Camel and other milk –-Natural Skin Maintenance. Rec Advances.309-338 In Keservani, R.K.; Sharma, A.K. & Kesharwani, R.K. (Eds.). Recent Advances in Drug Delivery Technology IGI Global. 510pp. https://doi.org/10.4018/978-1-5225-0754-3.ch011

Yateem, A.; Balba, M.T.; Al-Surrayai, T.; Al-Mutairi, B. & Al-Daher, R. (2008). Isolation of lactic acid bacteria with probiotic potential from camel milk. International Journal of Dairy Science., 3: 194-199.

Published

2020-10-20

How to Cite

Mohammadabadi, T. (2020). Camel Milk as an Amazing Remedy for Health Complications : A Review. Basrah J. Agric. Sci., 33(2), 125-137. https://doi.org/10.37077/25200860.2020.33.2.11

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Section

Review Articles