Main Article Content

Abstract

Pediocin is a low molecular weight (2.7-17 KDa) cationic molecules compose of a hydrophilic N-terminal part containing the pediocin box (YGNGV) motif and a hydrophobic or amphiphilic C-terminal variable part which is produced by some of Pediococcus bacteria. Pediocin has inhibition properties against several sensitive bacterial cells and acts on the cytoplasmic membrane during pores formation. Pediocin intervenes with the absorption of amino acids in phospholipids of cytoplasmic membrane from target cells. The pediocin molecule has unique properties such as the thermostability and detaining of activity at a wide pH values and resistance to some proteases enzymes. Pediocin has inhibition activity against many food spoilage bacteria and pathogenic bacteria including several bacterial genera such as ListeriaClostridiumBacillusAeromonas, Staphylocoocus, Lactobacillus and Enterococcus.  This  review will assist in learning the challenges that yet require to attention to apply pediocin in food industries as food preservative.

Keywords

Food preservative Pediococus Bacteriocin Pediocin antimicrobial

Article Details

How to Cite
Niamah, A. K. . (2018). Structure, mode of action and application of pediocin natural antimicrobial food preservative: A review. Basrah Journal of Agricultural Sciences, 31(1), 59–69. https://doi.org/10.37077/25200860.2018.76

References

  1. Abbas, B.A.; Ghadban, M.K. & Alghanim, A. M. (2017). Microbial evaluation of milk and milk products during a past two decades, in Basrah southern Iraq, a review. Annual Research & Review in Biology, 14(2): 1-8.
  2. Anastasiadou, S.; Papagianni, M.; Filiousis, G.; Ambrosiadis, I. & Koidis, P. (2008). Pediocin SA-1, an antimicrobial peptide from Pediococcus acidilactici NRRL B5627: Production conditions, purification and characterization. Bioresource Technol., 99(13): 5384-5390.
  3. Bhunia, A.K.; Johnson, M.C. & Ray, B. (1988). Purification, characterization and antimicrobial spectrum of a bacteriocin produced by Pediococcus acidilactici. Appl. Microbiol., 65(4): 261-268.
  4. Bhunia, A.K.; Johnson, M.C.; Ray, B. & Kalchayanand, N. (1991). Mode of action of pediocin AcH from Pediococcus acidilactici H on sensitive bacterial strains. Appl. Microbiol., 70(1): 25-33.
  5. Biswas, S.R.; Ray, P.; Johnson, M.C. & Ray, B. (1991). Influence of growth conditions on the production of a bacteriocin, pediocin AcH, by Pediococcus acidilactici H. Appl. Environ. Microbiol., 57(4): 1265- 1267.
  6. Castellano, P.; Pérez Ibarreche, M.; Blanco Massani, M.; Fontana, C. & Vignolo, G.M. (2017). Strategies for pathogen biocontrol using lactic acid bacteria and their metabolites: A focus on meat ecosystems and industrial environments. Microorganisms, 5(3): 38.
  7. Chikindas, M.L.; García-Garcerá, M.J.; Driessen, A.J.; Ledeboer, A.M.; Nissen- Meyer, J.; Nes, I.F.; Abee, T.; Konings, W.N. & Venema, G. (1993). Pediocin PA- 1, a bacteriocin from Pediococcus acidilactici PAC1. 0, forms hydrophilic pores in the cytoplasmic membrane of target cells. Appl. Environ. Microbiol., 59(11): 3577-3584.
  8. Christensen, D.P. & Hutkins, R.W. (1994). Glucose uptake by Listeria monocytogenes Scott A and inhibition by pediocin JD. Appl. Environ. Microbiol., 60(10): 3870-3873.
  9. Cintas, L.M.; Rodriguez, J.M.; Fernandez, M.F.; Sletten, K.; Nes, I.F.; Hernandez, P.E. & Holo, H. (1995). Isolation and characterization of pediocin L50, a new bacteriocin from Pediococcus acidilactici with a broad inhibitory spectrum. Appl. Environ. Microbiol., 61(7): 2643-2648.
  10. Cotter, P.D.; Hill, C. & Ross, R.P. (2005). Bacteriocins: developing innate immunity for food. Nat. Rev. Microbiol., 3(10): 777- 788.
  11. Cotter, P.D.; Ross, R.P. & Hill, C. (2013). Bacteriocins-a viable alternative to antibiotics. Nat. Rev. Microbiol., 11(2): 95-105.
  12. Daba, H.; Lacroix, C.; Huang, J.; Simard, R.E. & Lemieux, L. (1994). Simple method of purification and sequencing of a bacteriocin produced by Pediococcus acidilactici UL5. Appl. Bacteriol., 77(6): 682-688.
  13. Daeschel, M.A. & Klaenhammer, T.R. (1985). Association of a 13.6-megadalton plasmid in Pediococcus pentosaceus with bacteriocin activity. Appl. Environ. Microbiol., 50(6): 1538-1541.
  14. Díez, L.; Rojo-Bezares, B.; Zarazaga, M.; Rodríguez, J.M.; Torres, C. & Ruiz-Larrea, F. (2012). Antimicrobial activity of pediocin PA-1 against Oenococcus oeni and other wine bacteria. Food Microbial., 31(2): 167-172.
  15. Eijsink, V.G.; Axelsson, L.; Diep, D.B.; Håvarstein, L.S.; Holo, H. & Nes, I.F. (2002). Production of class II bacteriocins by lactic acid bacteria; an example of biological warfare and communication. Antonie Leeuwenhoek, 81(1-4): 639-654.
  16. Elegado, F.B.; Kim, W.J. & Kwon, D.Y. (1997). Rapid purification, partial characterization, and antimicrobial spectrum of the bacteriocin, Pediocin AcM, from Pediococcus acidilactici M. Int. J. Food Microbiol., 37(1): 1-11.
  17. Franz, C.M.; Vancanneyt, M.; Vandemeulebroecke, K.; De Wachter, M.; Cleenwerck, I.; Hoste, B.; Schillinger, U.; Holzapfel, W.H. & Swings, J. (2006). Pediococcus stilesii sp. nov., isolated from maize grains. Int. J. Syst. Evol. Microbiol., 56(2): 329-333.
  18. Gabrielsen, C.; Brede, D.A.; Nes, I.F. & Diep, D.B. (2014). Circular bacteriocins: biosynthesis and mode of action. Appl. Environ. Microbiol., 80(22): 6854-6862.
  19. Gonzalez, C.F. & Kunka, B.S. (1987). Plasmid-associated bacteriocin production and sucrose fermentation in Pediococcus acidilactici. Appl. Environ. Microbiol., 53(10): 2534-2538.
  20. Green, G.; Dicks, L.M.T.; Bruggeman, G.; Vandamme, E.J. & Chikindas, M.L. (1997). Pediocin PD?1, a bactericidal antimicrobial peptide from Pediococcus damnosus NCFB 1832. Appl. Microbiol., 83(1): 127-132.
  21. Haakensen, M.; Dobson, C.M.; Hill, J.E. & Ziola, B. (2009). Reclassification of Pediococcus dextrinicus (Coster and White 1964) Back 1978 (Approved Lists 1980) as Lactobacillus dextrinicus comb. nov., and emended description of the genus Lactobacillus Int. J. Syst. Evol. Microbiol., (3): 615-621.
  22. Jung, G. & Sahl, H.G. (1991) Lantibiotics: a survey. Pp: 1-34. In: Jung, G. and Sahl, H.G., (Eds.). Nisin and novel lantibiotics. ESCOM Science. 490pp.
  23. Kaur, G.; Singh, T.P.; Malik, R.K.; Bhardwaj, A. & De, S. (2014). Antibacterial efficacy of nisin, pediocin 34 and enterocin FH99 against L. monocytogenes, E. faecium and E. faecalis and bacteriocin cross resistance and antibiotic susceptibility of their bacteriocin resistant variants. J. Food Sci. & Tech., 51(2): 233-244.
  24. Kiran, F. & Osmanagaoglu, O. (2014). Inhibition of Listeria monocytogenes in chicken meat by pediocin AcH/PA-1 produced by Pediococcus pentosaceus OZF. Agro Food Industry Hi Tech., 25(6): 66-69.
  25. Kumar, Y.; Kaur, K.; Shahi, A. K.; Kairam, N. & Tyagi, S. K. (2017). Antilisterial, antimicrobial and antioxidant effects of pediocin and Murraya koenigii berry extract in refrigerated goat meat emulsion. LWT-Food Sci. & Tech., 79:135-144.
  26. Lewus, C.B.; Kaiser, A. & Montville, T.J. (1991). Inhibition of food-borne bacterial pathogens by bacteriocins from lactic acid bacteria isolated from meat. Appl. Environ. Microbiol., 57(6): 1683-1688.
  27. Mandal, B.A.R.N.A.L. I.; Chowdhury, R. A. N. J. A. N. A. & Jee, C.B. (2014).
  28. Purification and characterization of pediocin produced by Pediococcus acidilactici NCIM 2292. Int. J. Pharm. Sci., 6(6): 357-361.
  29. Mandal, V.; Sen, S.K., & Mandal, N.C. (2008). Optimized culture conditions for bacteriocin production by Pediococcus acidilactici LAB 5 and its characterization. Indian J. Biochem. Biophys., 45(2): 106-110.
  30. Mandal, V.; Sen, S.K. & Mandal, N.C. (2010). Assessment of antibacterial activities of pediocin produced by Pediococcus acidilactici LAB 5. J. Food Safety, 30(3): 635-651.
  31. Maqueda, M.; Gálvez, A.; Bueno, M.M.; Sanchez-Barrena, M.J.; González, C.; Albert, A.; Rico, M. & Valdivia, E. (2004). Peptide AS-48: prototype of a new class of cyclic bacteriocins. Curr. Protein Pept. Sc., 5(5): 399-416.
  32. Marwati, T., Richana, N., Harmayani, E., & Rahayu, E.S. (2017). Characterization of Pediocin PaF-11 from Pediococcus acidilactici F-11 as Biopreservatives. Proceedings of ICFSN, 37-40.
  33. Ming, X.; Weber, G.H.; Ayres, J.W. & Sanding, W.E. (1997). Bacteriocins applied to food packaging materials to inhibit Listeria monocytogenes on meats. J. Food Sci., 62(2):413-415.
  34. Montville, T.J. & Chen, Y. (1998). Mechanistic action of pediocin and nisin: Recent progress and unresolved questions. Appl. Microbiol. Biotech., 50(5): 511-519.
  35. Motlagh, A.M.; Holla, S.; Johnson, M.C.; Ray, B. & Field, R.A. (1992). Inhibition of Listeria spp. in sterile food systems by pediocin AcH, a bacteriocin produced by Pediococcus acidilactici H. J. Food Protect, 55(5): 337-343.
  36. Muriana, P.M. (1996). Bacteriocins for control of Listeria spp. in food. J Food Protect., 59(13): 54-63.
  37. Narsaiah, K.; Wilson, R.A.; Gokul, K.; Mandge, H.M.; Jha, S.N.; Bhadwal, S.; Anurag, R.K.; Malik, R.K. & Vij, S. (2015). Effect of bacteriocin-incorporated alginate coating on shelf-life of minimally processed papaya (Carica papaya L.). Postharvest Biol Technol., 100: 212-218.
  38. Niamah, A.K. (2010). Production of pediocin like bacteriocin from a local isolate of Pediococcus acidilactici and using it as foods preservative. Ph. D. Thesis, Coll. Agriculture, Univ. Basrah, 177pp.
  39. Niamah, A.K. (2012). Detection of Listeria monocytogenes bacteria in four types of milk using PCR. Pak. J. Nutr., 11(12): 1158-1160.
  40. Niamah, A.K. (2017). Physicochemical and microbial characteristics of yogurt with Added Saccharomyces boulardii. Curr. Res. Nut. Food Sci. J., 5(3): 300-307.
  41. Niamah, A. K.; Sahi, A.A. & Al-Sharifi, A.S. (2017a). Effect of feeding soy milk fermented by probiotic bacteria on some blood criteria and weight of experimental animals. Probiotics & Antimicrob. Prot., 9(3): 284-291.
  42. Niamah, A.K.; Al-Manhel, A.J. & Al-Shawi, M.J. (2017b). Isolation, purification and characterization of antimicrobial peptides produced from Saccharomyces boulardii. Int. J. Pept. Res. Ther., (In press).
  43. Niamah, A.K.; Al-Manhel, A.J. & Al-Shawi, M.J. (2017c). Study of inhibitory spectrum of metabolic extract from Saccharomyces boulardii yeast against some food related bacteria. Pak. J Food Sci., 25: 104-109.
  44. Nieto-Lozano, J.C.; Reguera-Useros, J.I.; Peláez-Martínez, M.D.C.; Sacristán-Pérez- Minayo, G.; Gutiérrez-Fernández, Á.J. & de la Torre, A.H. (2010). The effect of the pediocin PA-1 produced by Pediococcus acidilactici against Listeria monocytogenes and Clostridium perfringens in Spanish dry-fermented sausages and frankfurters. Food Control, 21(5): 679-685.
  45. Nilsen, T.; Nes, I.F. & Holo, H. (2003). Enterolysin A, a cell wall-degrading bacteriocin from Enterococcus faecalis LMG 2333. Appl. Environ. Microbiol., 69(5): 2975-2984.
  46. Osmanagaoglu, O.; Kiran, F. & Nes, I.F. (2011). A probiotic bacterium, Pediococcus pentosaceus OZF, isolated from human breast milk produces pediocin AcH/PA-1. Afr J Biotechnol., 10(11): 2070-2079.
  47. Perez, R.H.; Perez, M.T.M. & Elegado, F.B. (2015). Bacteriocins from lactic acid bacteria: a review of biosynthesis, mode of action, fermentative production, uses, and prospects. Phil Sci. Tech., 8(2): 61-67.
  48. Perez, R.H.; Zendo, T. & Sonomoto, K. (2014). Novel bacteriocins from lactic acid bacteria (LAB): Various structures and applications. Microb. Cell Fac., 13(1): S3. Doi:10.1186/1475-2859-13-S1-S3.
  49. Porto, M.C.W.; Kuniyoshi, T.M.; Azevedo, P.O.S.; Vitolo, M. & Oliveira, R.P.S. (2017). Pediococcus spp.: An important genus of lactic acid bacteria and pediocin producers. Biotechnol. Adv., 35(3): 361-374.
  50. Rodríguez, J.M.; Martínez, M.I. & Kok, J. (2002). Pediocin PA-1, a wide-spectrum bacteriocin from lactic acid bacteria. Crit. Rev. Food Sci., 42(2): 91-121.
  51. Sadishkumar, V. & Jeevaratnam, K. (2017). Purification and partial characterization of antilisterial bacteriocin produced by Pediococcus pentosaceus KJBC11 from Idli batter fermented with Piper betle leaves. J. Food Biochem., 42(1): 1-9.
  52. Schved, F.; Lalazar, A.; Henis, Y. & Juven, B.J. (1993). Purification, partial characterization and plasmid?linkage of pediocin SJ?1, a bacteriocin produced by Pediococcus acidilactici. Appl. Microbiol., 74(1): 67-77.
  53. Todorov, S.D. & Dicks, L.M. (2005). Pediocin ST18, an anti-listerial bacteriocin produced by Pediococcus pentosaceus ST18 isolated from boza, a traditional cereal beverage from Bulgaria. Process Biochemistry, 40(1): 365-370.
  54. Todorov, S.D.; Holzapfel, W. & Nero, L.A. (2016). Characterization of a novel bacteriocin produced by Lactobacillus plantarum ST8SH and some aspects of its mode of action. Ann microbial., 66(3): 949-962.
  55. Verma, S.K.; Sood, S.K.; Saini, R.K. & Saini, N. (2017). Pediocin PA-1 containing fermented cheese whey reduces total viable count of raw buffalo (Bubalis bubalus) milk. LWT-Food Sci. Tech., 83: 193-200.
  56. Wang, J.; Li, L.; Zhao, X. & Zhou, Z. (2015). Partial characteristics and antimicrobial mode of pediocin produced by Pediococcus acidilactici PA003. Ann. Microbial., (3):1753-1762.
  57. Woraprayote, W.; Malila, Y.; Sorapukdee, S.; Swetwiwathana, A.; Benjakul, S. & Visessanguan, W. (2016). Bacteriocins from lactic acid bacteria and their applications in meat and meat products. Meat Sci., 120: 118-132.
  58. Wu, C.W.; Yin, L.J. & Jiang, S.T. (2004). Purification and characterization of bacteriocin from Pediococcus pentosaceus ACCEL. J Agr. Food Chem., 52(5): 1146- 1151.