Main Article Content
Abstract
The presence of Antibacterial in the aquatic environment is a major concern because of the effect of Antibacterial on water quality, aquatic organisms and human health. The current study aims to detect Antibacterial (Amoxicillin, Ciprofloxacin, and Levofloxacin) seasonally in water, sediments, muscles and liver of Nile tilapia fish during the period from November 2020 to August 2021 in two selected stations in Shatt Al-Arab, Basrah, Iraq. The samples were analyzed using high performance liquid chromatography (HPLC), High concentrations of the antibiotic Ciprofloxacin (CIP) were recorded in each of the water, sediment and fish muscle samples during the spring season at the second station, reaching the 24.9 mg l1-, 24.5 mg. kg1-, 7.4 mg. kg1-, respectively, while the high concentration of Amoxicillin )AMO( Antibacterial was 4.1 mg.kg-1 in liver of fish in spring season in the second station. The presence of Antibacterial in the aquatic environment in such high concentrations is a source of great concern. The study recommends conducting more studies to measure Antibacterial contamination in other areas of the Shatt al-Arab and the Iraqi marshes.
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References
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References
Abdullah, A. D., Masih, I., van der Zaag, P., Karim, U. F.A., Popescu, I., & Al Suhail, Q. (2015). Shatt Al Arab River system under escalating pressure: a preliminary exploration of the issues and options for mitigation. International Journal of River Basin Management, 13(2), 215-227.
https://doi.org/10.1080/15715124.2015.1007870
Ahmed M.H., Resen A.K., & Al-Niaeem K.S. (2022). Supplementary Information. Zenodo.
https://doi.org/10.5281/zenodo.7042396
Al-Khafaji, B. Y., Mohammed, A. B., & Maqtoof, A. A. (2011). Distribution of some heavy metals in water, sediment & fish Cyprinus carpio in Euphrates river near Al- Nassiriya city center south Iraq. Baghdad Science Journal, 8(1), 552-560.
https://doi.org/10.21123/bsj.2011.8.1.552-560
Al-Khazrajy, O. S. A., & Boxall, A. B. A. (2016). Impacts of compound properties and sediment characteristics on the sorption behaviour of pharmaceuticals in aquatic systems. Journal of Hazardous Materials, 317, 198-209.
https://doi.org/10.1016/j.jhazmat.2016.05.065
Al-Mahmood, H. K. H., Al-Sayaab, H. A., Al-Miahi, D. S. B., Mahmoud, A. B., & Mutasher, W. R. (2011). One dimensional model to study hydrodynamics properties for north part of Shatt Al Arab River (south Iraq). Basrah Journal of Science, 28(1), 1-14.
Anh, H. Q., Le, T. P. Q., Da Le, N., Lu, X. X., Duong, T.T., Garnier, J., & Nguyen, T. A. H. (2020). Antibiotics in surface water of East and Southeast Asian countries: A focused review on contamination status, pollution sources, potential risks, and future perspectives. Science of The Total Environment, 142865.
https://doi.org/10.1016/j.scitotenv.2020.142865
Bilal, M., Mehmood, S., Rasheed, T., & Iqbal, H. M. N. (2020). Antibiotics traces in the aquatic environment: persistence and adverse environmental impact. Current Opinion in Environmental Science and Health, 13, 68-74.
https://doi.org/10.1016/j.coesh.2019.11.005
Blackwell, P. A., Boxall, A. B. A., Kay, P., & Noble, H. (2005). Evaluation of a lower tier exposure assessment model for veterinary medicines. Journal of Agricultural and Food Chemistry, 53(6), 2192-2201.
https://doi.org/10.1021/jf049527b
Bojarski, B., & Witeska, M. (2020). Blood biomarkers of herbicide, insecticide, and fungicide toxicity to fish: A review. Environmental Science and Pollution Research, 27, 19236-19250.
https://doi.org/10.1007/s11356-020-08248-8
Cheng, D., Liu, X., Zhao, S., Cui, B., Bai, J., & Li, Z. (2017). Influence of the natural colloids on the multi-phase distributions of antibiotics in the surface water from the largest lake in North China. Science of the Total Environment, 578, 649-659.
https://doi.org/10.1016/j.scitotenv.2016.11.012
Cui, C., Han, Q., Jiang, L., Ma, L., Jin, L., Zhang, D., & Zhang, T. (2018). Occurrence, distribution, and seasonal variation of antibiotics in an artificial water source reservoir in the Yangtze River delta, East China. Environmental Science and Pollution Research, 25(20), 19393-19402.
https://doi.org/10.1007/s11356-018-2124-x
Grenni, P., Ancona, V., & Barra Caracciolo, A. (2018). Ecological effects of antibiotics on natural ecosystems: A review. Microchemical Journal, 136, 25-39.
https://doi.org/10.1016/j.microc.2017.02.006
Gros, M., Petrovi M. C., & Barcel, D. O. (2006). Development of amultiresidue analytical methodology based on liquid chromatography–tandem mass spectrometry (LC–MS/MS) for screening and trace level determination of pharmaceuticals in surface and waste waters, Talanta, 70(4), 678-690.
https://doi.org/10.1016/j.talanta.2006.05.024
Hamscher, G., Sczesny, S., Hoper, H., & Nau, H. (2002). Determination of persistent tetracycline residues in soil fertilized with liquid manure by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry. Analytical Chemistry, 74(7), 1509-1518.
https://doi.org/10.1021/ac015588m
Lee, S., Kim, C., Liu, X., Lee, S., Kho, Y., Kim, W. K., Kim, P., & Choi, K. (2021). Ecological risk assessment of amoxicillin, enrofloxacin, and neomycin: Are their current levels in the freshwater environment safe? Toxics, 9(8), 196.
https://doi.org/10.3390/toxics9080196
Li, B. & Zhang, T. (2010). Biodegradation and adsorption of antibiotics in theactivated sludge process. Environmental Science and Technology, 44, 3468-3473.
https:// oi.org/10.1021/es903490h
Li, J. & Cui, M. (2020). Kinetic study on the sorption and degradation of antibiotics in the estuarine water: an evaluation based on single and multiple reactions. Environmental Science and Pollution Research, 27(33), 42104-42114.
https://doi.org/10.1007/s11356-020-10194-4
Mahmood, A.R., Al-Haideri, H. H., & Hassan, F. M. (2019). Detection of antibiotics in drinking water treatment plants in Baghdad City, Iraq. Advances in Public Health, Article ID 7851354, 10pp.
https://doi.org/10.1155/2019/7851354
Naveed, S., Sultana, N., Arayne, M. S., & Dilshad, H. D. (2014). A new HPLC method for the assay of levofloxacin and its application in drug-metal interaction studies. Journal of Scientific and Innovative Research, 3(1), 91-96.
Ngigi, A. N., Magu, M. M., & Muendo, B. M. (2019). Occurrence of antibiotics residues in hospital wastewater, wastewater treatment plant, and in surface water in Nairobi County, Kenya. Environmental Monitoring and Assessment, 192(1).
https://doi.org/10.1007/s10661-019-7952-8
Qiao, M., Ying, G. G., Singer, A. C., & Zhu, Y. G. (2018). Review of antibiotic resistance in China and its environment. Environment International, 110, 160-172.
https://doi.org/10.1016/j.envint.2017.10.016
Reddy, M. S., Mehta, B., Dave, S., Joshi, L., Karthikeyan, V. K. S., Sarma, S., Basha, G. R., & Bhatt, P. (2007). Bioaccumulation of heavy metals in some commercial fishes and crabs of the Gulf of Cambay, India. Current Science, 92, 1489-1491.
Thakare, R., Kesharwani, P., Dasgupta, A., Srinivas, N., & Chopra, S. (2020). Chapter 1, Antibiotics: past, present, and future. Pp, 1-8. In: Kesharwani, P., Chopra, S., & Dasgupta, A. (Eds.), Drug Discovery Targeting Drug-Resistant Bacteria. Academic Press. 407pp.
https://doi.org/10.1016/B978-0-12-818480-6.00001-1
Torres, N. H., de Salles Pupo, M. M., Ferreira, L. F. R., Maranho, L. A., Americo-Pinheiro, J. H. P., Vilca, F. Z., & Tornisielo, V. L. (2017). Spatial and seasonal analysis of antimicrobials and toxicity tests with Daphnia magna, on the sub-basin of Piracicaba river, SP, Brazil. Journal of Environmental Chemical Engineering, 5(6), 428 6070-6076.
https://doi.org/10.1016/j.jece.2017.11.031
Unutkan, T., Bakırdere, S., & Keyf, S. (2018). Development of an analytical method for the determination of amoxicillin in commercial drugs and wastewater Samples, and assessing its stability in simulated gastric digestion. Journal of Chromatographic Science, 56(1), 36-40.